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Dynamic protein methylation in chromatin biology

October 16, 2008

Ng, S. S., Yue, W. W., Oppermann, U. and Klose, R. J. (2009) Dynamic protein methylation in chromatin biology. Cell Mol Life Sci. 66, 407-422

http://link.springer.com/article/10.1007%2Fs00018-008-8303-z

MeCP2 Binding to DNA Depends upon Hydration at Methyl-CpG

February 29, 2008

Ho, K. L., McNae, I. W., Schmiedeberg, L., Klose, R. J., Bird, A. P. and Walkinshaw, M. D. (2008) MeCP2 binding to DNA depends upon hydration at methyl-CpG. Mol Cell. 29, 525-531

http://www.sciencedirect.com/science/article/pii/S1097276508000968

Histone H3 Arg2 methylation provides alternative directions for COMPASS

November 14, 2007

Klose, R. J. and Zhang, Y. (2007) Histone H3 Arg2 methylation provides alternative directions for COMPASS. Nat Struct Mol Biol. 14, 1058-1060

http://www.nature.com/nsmb/journal/v14/n11/full/nsmb1107-1058.html

Demethylation of Histone H3K36 and H3K9 by Rph1: a Vestige of an H3K9 Methylation System in Saccharomyces cerevisiae?

June 5, 2007

Klose, R. J., Gardner, K. E., Liang, G., Erdjument-Bromage, H., Tempst, P. and Zhang, Y. (2007) Demethylation of histone H3K36 and H3K9 by Rph1: a vestige of an H3K9 methylation system in Saccharomyces cerevisiae? Mol Cell Biol. 27, 3951-3961

http://mcb.asm.org/content/27/11/3951.long

PLU-1 Is an H3K4 Demethylase Involved in Transcriptional Repression and Breast Cancer Cell Proliferation

March 23, 2007

Yamane, K., Tateishi, K., Klose, R. J., Fang, J., Fabrizio, L. A., Erdjument-Bromage, H., Taylor-Papadimitriou, J., Tempst, P. and Zhang, Y. (2007) PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation. Mol Cell. 25, 801-812

http://www.sciencedirect.com/science/article/pii/S1097276507001463

The trithorax-group protein Lid is a histone H3 trimethyl-Lys4 demethylase

March 11, 2007

Lee, N., Zhang, J., Klose, R. J., Erdjument-Bromage, H., Tempst, P., Jones, R. S. and Zhang, Y. (2007) The trithorax-group protein Lid is a histone H3 trimethyl-Lys4 demethylase. Nat Struct Mol Biol. 14, 341-343

http://www.nature.com/nsmb/journal/v14/n4/full/nsmb1216.html

The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase

March 9, 2007

Klose, R. J., Yan, Q., Tothova, Z., Yamane, K., Erdjument-Bromage, H., Tempst, P., Gilliland, D. G., Zhang, Y. and Kaelin, W. G., Jr. (2007) The retinoblastoma binding protein RBP2 is an H3K4 demethylase. Cell. 128, 889-900

http://www.sciencedirect.com/science/article/pii/S0092867407001948

Regulation of histone methylation by demethylimination and demethylation

March 7, 2007

Klose, R. J. and Zhang, Y. (2007) Regulation of histone methylation by demethylimination and demethylation. Nat Rev Mol Cell Biol. 8, 307-318

http://www.nature.com/nrm/journal/v8/n4/full/nrm2143.html

Yeast Jhd2p is a histone H3 Lys4 trimethyl demethylase

February 18, 2007

Liang, G., Klose, R. J., Gardner, K. E. and Zhang, Y. (2007) Yeast Jhd2p is a histone H3 Lys4 trimethyl demethylase. Nat Struct Mol Biol. 14, 243-245

http://www.nature.com/nsmb/journal/v14/n3/full/nsmb1204.html

JmjC-domain-containing proteins and histone demethylation

September 1, 2006

Klose, R. J., Kallin, E. M. and Zhang, Y. (2006) JmjC-domain-containing proteins and histone demethylation. Nat Rev Genet. 7, 715-727

http://www.nature.com/nrg/journal/v7/n9/full/nrg1945.html

The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36

May 28, 2006

Klose, R. J., Yamane, K., Bae, Y., Zhang, D., Erdjument-Bromage, H., Tempst, P., Wong, J. and Zhang, Y. (2006) The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36. Nature. 442, 312-316

http://www.nature.com/nature/journal/v442/n7100/full/nature04853.html

Genomic DNA methylation: the mark and its mediators

February 1, 2006

Klose, R. J. and Bird, A. P. (2006) Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci. 31, 89-97

http://www.sciencedirect.com/science/article/pii/S096800040500352X

DNA Binding Selectivity of MeCP2 Due to a Requirement for A/T Sequences Adjacent to Methyl-CpG

September 2, 2005

Klose, R. J., Sarraf, S. A., Schmiedeberg, L., McDermott, S. M., Stancheva, I. and Bird, A. P. (2005) DNA binding selectivity of MeCP2 due to a requirement for A/T sequences adjacent to methyl-CpG. Mol Cell. 19, 667-678

http://www.sciencedirect.com/science/article/pii/S1097276505015091

MeCP2 Behaves as an Elongated Monomer That Does Not Stably Associate with the Sin3a Chromatin Remodeling Complex

August 18, 2004

Klose, R. J. and Bird, A. P. (2004) MeCP2 behaves as an elongated monomer that does not stably associate with the Sin3a chromatin remodeling complex. J Biol Chem. 279, 46490-46496

http://www.jbc.org/content/279/45/46490.long

Characterization of an Overexpressed Spindle Protein during a Baculovirus Infection

March 1, 2000

Li, X., Barrett, J., Pang, A., Klose, R. J., Krell, P. J. and Arif, B. M. (2000) Characterization of an overexpressed spindle protein during a baculovirus infection. Virology. 268, 56-67

http://www.sciencedirect.com/science/article/pii/S0042682299901381

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Klose Group
Department of Biochemistry
Oxford University
Oxford, UK
OX1 3QU

+44 (0)1865 613 200

rob.klose@bioch.ox.ac.uk

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