Klose Lab News
Publication – Polycomb repressive complex 1 shapes the nucleosome landscape but not accessibility at target genes.
Congratulations to Hamish, Nadya and Neil for their latest publication in Genome Research!
Publication – FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment
Congratulations to Emilia and Angelika for their latest publication in eLife!
Check it out here:
Welcome to our new PhD student Deniz!
Welcome!
Rob is awarded an Investigator Award by the Wellcome Trust
Congratulations to Rob for his Wellcome Investigator Award! New Postdoc positions will be advertised soon.
Welcome to our new Part II students Alex and Hiro!
Welcome!
Publication – The SET1 Complex Selects Actively Transcribed Target Genes via Multivalent Interaction with CpG Island Chromatin
Congratulations to Dave, Vincenzo and all of the co-authors for their latest publication in Cell Reports!
https://www.ncbi.nlm.nih.gov/pubmed/28877467
https://www.cell.com/cell-reports/fulltext/S2211-1247(17)31137-3
Rob is awarded Chair of Genetics at Keble
Congratulations to Rob, who has just been appointed as Chair of Genetics in the Department of Biochemistry. He will be a fellow of Keble College.
Dr Paula Dobrinic joins the lab!
Welcome to Paula, who is joining us from Vlatka Zoldos’s lab at the University of Zagreb, Croatia. She will be investigating how CpG islands contribute to gene regulation.
Publication – The pioneer factor OCT4 requires the chromatin remodeller BRG1 to support gene regulatory element function in mouse embryonic stem cells
Congratulations to Hamish for the acceptance of his paper in eLIFE!
Check it out here:
Publication – RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes
Congratulations to Nathan, Hamish and all of the co-authors for their latest publication in eLIFE!
Read the full article here:
Anne wins prize for DPhil talk
Congratulations to Anne for being awarded a prize for her presentation at the Department of Biochemistry DPhil Symposium.
Welcome to our new Part II students Praveen and Jess!
Welcome!
Dr Mariya Georgieva joined the lab!
Welcome!
Publication – REVIEW Histone demethylases in chromatin biology and beyond
Emilia and Anne’s review article discussing the varied roles of histone demethylases is now online!
Check out the full review here:
Rob gives 2015 Francis Crick Lecture at the Royal Society
This evening Rob gave the 2015 Francis Crick Lecture at the Royal Society in London. Congratulations to Rob for a fantastic talk!
Hamish wins prize for DPhil talk
Congratulations to Hamish for being awarded a prize for his presentation at the Department of Biochemistry DPhil Symposium.
Publication – REVIEW Targeting Polycomb systems to regulate gene expression
Neil and Nathan’s review article on polycomb targeting is now available online! Well done to Neil and Nathan for their hard work.
Check out the full review here:
http://www.nature.com/nrm/journal/vaop/ncurrent/abs/nrm4067.html
Conference – 40th FEBS Congress
Vincenzo recently won a travel grant to attend the 15th FEBS Young Scientists’ Forum, joined with the 40th FEBS Congress in Berlin, where he was given the opportunity to present his work. Well done to Vincenzo!
Conference – Oxford Transcription Meeting 2015
Rob and other lab members attended the inaugural Oxford Transcription Meeting, at the Oxford Martin School here in Oxford. The meeting brought together groups studying chromatin and transcription from different deparments within the university.
Angelika is awarded EMBO Fellowship
Congratulations to Angelika for being awarded an EMBO fellowship to pursue her work in the lab. Her award is to investigate the different regulatory inputs for different classes of vertebrate gene promoters.
Well done Angelika!
Anca wins top CRUK Prize
Anca Farcas, former DPhil student in the lab, is the joint winner of Cancer Research UK (CRUK) 2014 Pontecorvo Prize.
The prize is awared to the CRUK-funded student who produced the best PhD thesis and made the most outstanding contribution to scientific knowledge in their field of research.
This a great recognition of all of Anca’s hard work in the lab. Congratulations Anca!
Klose Lab Retreat 2015 – Niederau, Austria
The Klose lab has returned safely from another highly successful lab retreat. Based in the small Austrian village Niederau, the retreat proved to be stimulating scientifically and socially within the lab. When the lab wasn’t discussing science, we made the most of the fantastic weather and spent time enjoying the fantastic mountain scenery (and the ski slopes!).
Dave passed his DPhil viva!
Congratulations to Dave for passing his DPhil viva!
Well done Dr Brown!
Dr Angelika Feldmann joined the lab!
Angelika is joining us from Dirk Schubeler’s lab at the FMI, Basel. She will be focusing on the mechanisms by which different promoter classes coordinate their regulatory inputs in vertebrates.
Conferences – EMBO Transcription and Chromatin, and CSHL Epigenetics and Chromatin
Lab members attended two conferences recently.
Hamish attended the EMBO Transcription and Chromatin conference in Heidelberg, Germany, where he presented a poster.
Rob and Neil also attended the Cold Spring Harbor Laboratory Epigenetics and Chromatin conference in the US, where Rob presented the latest work from the lab on polycomb recruitment.