2014 Publications
2014
Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment
Cooper, S., Dienstbier, M., Hassan, R., Schermelleh, L., Sharif, J., Blackledge, N.P., De Marco, V., Elderkin, S., Koseki, H., Klose, R., Heger, A., Brockdorff, N. Targeting Polycomb to Pericentric Heterochromatin in Embryonic Stem Cells Reveals a Role for H2AK119u1 in PRC2 Recruitment. Cell Reports. 7 (5), 1456-1470
http://www.sciencedirect.com/science/article/pii/S221112471400299X
Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation
Blackledge, N.P., Farcas, A.M., Kondo, T., King, H.W., McGouran, J.F., Hanssen, L.L., Ito, S., Cooper, S., Kondo, K., Koseki, Y., Ishikura, T., Long, H.K., Sheahan, T.W., Brockdorff, N., Kessler, B.M., Koseki, H., Klose, R.J. (2014) Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation. Cell. 157 (6), 1445-1459
http://www.sciencedirect.com/science/article/pii/S0092867414005893
Understanding the relationship between DNA methylation and histone lysine methylation
Rose, N. R. and Klose R. J. Understanding the relationship between DNA methylation and histone lysine methylation. Biochimica et Biophysica Acta (BBA) – Gene Regulatory Mechanisms. 1839 (12), 1362-1372
http://www.sciencedirect.com/science/article/pii/S1874939914000285