2024 Publications
2024
The PNUTS phosphatase complex controls transcription pause release
Kelley JR, Dimitrova E, Maciuszek M, Nguyen HT, Szczurek AT, Hughes AL, Blackledge NP, Kettenbach AN, Klose RJ.
Molecular Cell, 2024.
Epi-microRNA mediated metabolic reprogramming counteracts hypoxia to preserve affinity maturation
Nakagawa R, Llorian M, Varsani-Brown S, Chakravarty P, Camarillo JM, Barry D, George R, Blackledge NP, Duddy G, Kelleher NL, Klose RJ, Turner M, Calado DP.
Nature Communications, 2024.
The Polycomb system sustains promoters in a deep OFF state by limiting pre-initiation complex formation to counteract transcription
Szczurek AT, Dimitrova E, Kelley JR, Blackledge NP, Klose RJ.
Nature Cell Biology 2024
Extensive DNA methylome rearrangement during early lamprey embryogenesis.
Angeloni A, Fissette S, Kaya D, Hammond JM, Gamaarachchi H, Deveson IW, Klose RJ, Li W, Zhang X, Bogdanovic O.
Nat Communication 2024.